Found 59 matching trials
ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia PHASE1 This phase Ib/II trial studies the side effects and best dose of FT-2102 wh...
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Multiple Locations
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Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma PHASE1 This phase I trial tests the safety, side effects, and best dose of nivolum...
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University of Alabama at Birmingham Cancer Center
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Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma PHASE2 This phase II trial studies the effect of belinostat and SGI-110 (guadecita...
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Active Not Recruiting
Location
Mayo Clinic Hospital in Arizona
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ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic Phase PHASE2 This phase II trial studies the effect of ASTX727 and dasatinib in treating...
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Active Not Recruiting
Location
M D Anderson Cancer Center
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Effect of Food on Blood Levels of ASTX727 PHASE1 This study is designed to examine blood levels of ASTX727, a fixed-dose com...
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A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) PHASE1 To evaluate the safety, pharmacokinetics (PK), and efficacy of ASTX660 when...
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University of California San Francisco
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A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation PHASE2 To learn if ASTX727 given alone or in combination with donor lymphocyte inf...
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MD Anderson Cancer Center
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A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST) PHASE2 The purpose of this study is to see whether the study drug ASTX727 is an ef...
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
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Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia PHASE2 This phase II trial studies the effects of venetoxlax in combination with d...
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Active Not Recruiting
Location
M D Anderson Cancer Center
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Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment PHASE1 This is a Phase 1b, multicenter, open-label, pharmacokinetic (PK), and safe...
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